Daily Dose Q&A
2026-06-11
What medications are considered first line drugs for the prophylaxis treatment of cannabinoid hyperemesis syndrome (CHS)?
Tricyclic antidepressants (TCAs) are considered to be first-line drugs for the prophylaxis of CHS and CVS. TCAs, such as amitriptyline, may mitigate withdrawal effects of cannabis, and may reduce the duration, severity, and frequency of CHS episodes, and they also decrease the number of emergency department visits and hospitalizations. Results from retrospective and open label trials suggest that amitriptyline is effective in approximately 70% of patients.Loganathan, P., Gajendran, M., & Goyal, H. (2024). A Comprehensive Review and Update on Cannabis Hyperemesis Syndrome. Pharmaceuticals, 17(11), 1549. https://doi.org/10.3390/ph17111549 and Jiménez Castillo, R. A., et al. (2025). Cannabinoid hyperemesis syndrome: A review. Revista de Gastroenterología de México. https://www.sciencedirect.com/science/article/pii/S2255534X25000581
2026-06-10
How long does it take to achieve complete recovery from cannabis use disorder?
The duration to achieve complete recovery from cannabis use disorder may range from a minimum of 3 months to up to 4 years. This variability in recovery time is partly attributable to its accumulation in adipose tissue and due to the extended half-life of THC.Loganathan, P., Gajendran, M., & Goyal, H. (2024). A Comprehensive Review and Update on Cannabis Hyperemesis Syndrome. Pharmaceuticals, 17(11), 1549. https://doi.org/10.3390/ph17111549 and Jiménez Castillo, R. A., et al. (2025). Cannabinoid hyperemesis
2026-06-09
If an individual previously diagnosed with cannabis use disorder has not met any of the diagnostic criteria (other than craving) for the past 8 months starts using cannabis once per month, can the individual still be considered to be in remission?
Yes. Remission is based on whether the criteria for CUD are still being met and not on whether the individual is using cannabis. A person may use cannabis during the remission period as long as that use does not meet any of the diagnostic criteria for the disorder, (with the exception of craving).American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed., text rev.; DSM-5-TR). American Psychiatric Publishing. ISBN: 978-0-89042-575-6.
2026-06-08
What are the criteria for sustained remission of cannabis use disorder?
Sustained remission applies when none of the diagnostic criteria for cannabis use disorder have been met (with the exception of craving) for a continuous period of 12 months or longer. American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed., text rev.; DSM-5-TR). American Psychiatric Publishing. ISBN: 978-0-89042-575-6.
2026-06-05
What are the criteria for early remission of cannabis use disorder?
Early remission applies when an individual who was previously diagnosed with cannabis use disorder has not met any of the diagnostic criteria (except for craving) for a period of at least 3 months but less than 12 months. American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders (5th ed., text rev.; DSM-5-TR). American Psychiatric Publishing. ISBN: 978-0-89042-575-6.