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Does hyperglycemia impact expression of CB2 receptors in the glomerulus of the kidney?
Yes – Hyperglycemia, as well as high urinary albumin levels, downregulate the expression of CB2 receptors in the glomerulus and proximal tubule cells. This downregulation plays a role in the progression of diabetic nephropathy.
Meah, F., Lundholm, M., Emanuele, N. et al. The effects of cannabis and cannabinoids on the endocrine system. Rev Endocr Metab Disord (2021). Aug 30, 2021.
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