Daily Dose Q&A - The Answer Page

2026-03-16

Have any studies compared chronic pain patients' scheduling of THC administration to that of CBD administration?

According to a survey involving 1087 adults with chronic pain, "THC-rich products were typically used at night, while CBD-rich products were more often used during the day."

Boehnke KF, Yakas L, Scott JR, DeJonckheere M, Litinas E, Sisley S, Clauw DJ, Williams DA, McAfee J. A mixed methods analysis of cannabis use routines for chronic pain management. J Cannabis Res. 2022 Jan 11;4(1):7.

2026-03-13

Have any studies found that some modes of cannabinoid administration are more effective than others for the treatment of pain?

According to a survey involving 1087 adults with chronic pain, "participants using non-inhalation + inhalation administration routes reported larger improvements in health than the non-inhalation... and inhalation subgroups. Similarly, the non-inhalation + inhalation group had significantly more medication substitutions than those using just non-inhalation.... and inhalation administration routes, respectively."

Boehnke KF, Yakas L, Scott JR, DeJonckheere M, Litinas E, Sisley S, Clauw DJ, Williams DA, McAfee J. A mixed methods analysis of cannabis use routines for chronic pain management. J Cannabis Res. 2022 Jan 11;4(1):7.

2026-03-12

Which cannabinoid administration routine for the treatment of chronic pain is most often employed... non-inhalation, inhalation or a combination of both?

According to a survey involving just over 1000 adults with chronic pain using cannabis for symptom management in the USA and Canada, 18.8%, 36.2%, and 45% used non-inhalation, inhalation, and non-inhalation + inhalation routes, respectively. Those who used inhalation routes were younger, while a higher proportion of those who used non-inhalation routes were female."

Boehnke KF, Yakas L, Scott JR, DeJonckheere M, Litinas E, Sisley S, Clauw DJ, Williams DA, McAfee J. A mixed methods analysis of cannabis use routines for chronic pain management. J Cannabis Res. 2022 Jan 11;4(1):7.

2026-03-11

Other than abdominal pain and nausea, what IBD symptoms seem to be relieved by the use of medical cannabis?

According to numerous clinical trials, some survey studies and multiple observational studies, IBD patients find symptomatic improvement of abdominal pain, diarrhea, insomnia, anxiety, nausea, poor appetite, and fatigue when using cannabinoid therapy.

Greywoode R, Cunningham C, Hollins M, Aroniadis O. Medical Cannabis Use Patterns and Adverse Effects in Inflammatory Bowel Disease. J Clin Gastroenterol. 2022 Oct 14.

2026-03-10

Some CBD manufacturers use solvents to extract the CBD and other plant components. The presence or absence of which solvents are often reported on a certificate of analysis of a CBD product?

Some of the solvents typically reported on a CoA of CBD products include acetone, benzene, butane, chloroform, cyclohexane, ethanol, heptane, hexane, isopropyl alcohol, methanol, pentane, propane, toluene, and xylenes.

Certificates of Analysis of various CBD products.