Your Dose of Cannabis Education

Your Dose of Cannabis Education

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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education

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2024-06-12
Are cannabinoid receptors present on skin cells?
Yes. Cannabinoid receptors are present on many types of skin cells, including keratinocytes and fibroblasts. The results of preliminary studies evaluating the effects of cannabis extracts on skin cells indicate that hemp extracts may reduce oxidative stress, inhibit skin aging processes and positively affect the viability of skin cells. Analyses also showed that hydrogels based on cannabis extracts have a positive effect on skin hydration.
Zagórska-Dziok,M.; Bujak, T.; Ziemlewska, A.; Nizioł-Łukaszewska, Z. Positive Effect of Cannabis sativa L. Herb Extracts on Skin Cells and Assessment of Cannabinoid-Based Hydrogels Properties. Molecules 2021, 26, 802. https://doi.org/10.3390/ molecules26040802
2024-06-11
What cardiac events have been seen in pediatric patients who consume edible recreational cannabis?
According to a retrospective analysis of the National Poison Data System, data for pediatric exposures to edible cannabis products in children <6 years from 2017 to 2021, involving 7043 exposures, "tachycardia was seen in 548 cases (11.4%), whereas bradycardia was seen in 68 cases (1.4%)... Hypotension, in 123 cases (2.5%), was more common than hypertension, 43 cases (0.9%)."
Tweet MS, Nemanich A, Wahl M. Pediatric Edible Cannabis Exposures and Acute Toxicity: 2017–2021. Pediatrics. 2023;151(2):e2022057761
2024-06-10
If a parturient consumes cannabis, does THC get excreted in the breastmilk?
Yes, and in fact, "THC can be found in breast milk for up to 6 days after maternal consumption, [and ]it may be concentrated up to sevenfold compared with maternal plasma in chronic consumption....The relative infant dose, the amount absorbed, has been estimated to be 2.5% (range 0.4%–8.7%) of the maternal dose."
Shah S, Schwenk ES, Sondekoppam RV, et al ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids Regional Anesthesia & Pain Medicine Published Online First: 03 January 2023. doi: 10.1136/rapm-20
2024-06-09
Does cannabis use impact thermoregulation? Is cannabis use associated with hypothermia or hyperthermia in the post-operative period?
"Cannabinoid use may be associated with postoperative hypothermia, shivering and increased platelet aggregation. Temperature regulation may be affected by CB1 receptor agonism, especially with chronic, high-quantity use." However, it has also been noted that some "parturients consuming high quantities of potent THC formulations may present with fever, tachycardia, and hypertension."
Shah S, Schwenk ES, Sondekoppam RV, et al ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids Regional Anesthesia & Pain Medicine Published Online First: 03 January 2023. doi: 10.1136/rapm-20
2024-06-08
What are the acute cardiovascular effects of smoked cannabis in individuals who have only started smoking cannabis recently?
"In new users, the acute effects following cannabis smoking result in an increase in heart rate and blood pressure initially within the first 60 min from ß-adrenergic stimulation and parasympathetic inhibition, followed by norepinephrine-mediated increases in heart rate and blood pressure for up to 120 min following cannabis use."
Shah S, Schwenk ES, Sondekoppam RV, et al ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids Regional Anesthesia & Pain Medicine Published Online First: 03 January 2023. doi: 10.1136/rapm-20

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