Your Dose of Cannabis Education
Your Dose of Cannabis Education
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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education.
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No. In a study evaluating abuse liability of CBD, it was found that “abrupt withdrawal of CBD after 4 weeks of use (750 mg twice daily taken orally) did not result in any symptoms of physical withdrawal.” Unlike THC, CBD is not addictive. The specific psychological health conditions for which CBD is being evaluated include schizophrenia and bipolar disorder, adjunct treatment in early psychosis, anxiety and insomnia, treatment-resistant depression, PTSD (CBD+THC), ADHD (CBD+THC), and panic disorder. Also, use disorders, including cannabis use disorder, alcohol use disorder, and opioid use disorder are being studied.According to a British Medical Journal (BMJ) article, "THC inhibits glutamate and 5-hydroxytryptamine release and increases dopamine secretion. CBD enhances adenosine receptor signaling, and decreases reactive oxygen species, tumour necrosis factor, and T cell proliferation, without the psychoactive effects of THC. The multifaceted analgesic and anti-inflammatory properties of cannabinoids may positively influence the perception of pain across different conditions." (BMJ)“The major components of the endocannabinoid system in the brain, including functional CB1 receptors and the endocannabinoids 2-AG and AEA, are present around gestational week 19 in humans and likely have a role in critical early behavior processes... This system may also contribute to the proper formation, growth, migration, and wiring of various areas in the developing fetal brain. The expression of the CB1 receptor in the brain also changes throughout human development. Both the expression levels and locations of expression differ greatly between fetal brain development and early life when compared to adult brains.”The activation of CB2 receptors results in various outcomes, including the inhibition of pro-inflammatory cytokine production and migration of immune cells (neutrophil and macrophages). As a result of these effects, chronic pain may be reduced.
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CBD in Clinical Care V2
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