Your Dose of Cannabis Education

Your Dose of Cannabis Education

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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education

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2025-11-07
Has any national drug administration approved a CBD-containing product for therapeutic use in conditions other than epilepsy?
Yes. The oromucosal spray Sativex (nabiximols) is a cannabis extract that contains the principal cannabinoids delta-9-tetrahydrocannibinol (THC) and cannabidiol (CBD) in a 50:50 ratio, as well as specific minor cannabinoids and other non-cannabinoid components. Regulatory approval has been obtained in numerous countries outside the United States for the treatment of multiple sclerosis symptoms (nerve pain, spasticity, overactive bladder, and other symptoms).
GW Pharmaceuticals website. Sativex. https://www.gwpharm.com/healthcare-professionals/sativex
2025-11-06
If a parturient consumes cannabis, does THC get excreted in the breastmilk?
Yes, and in fact, "THC can be found in breast milk for up to 6 days after maternal consumption, [and ]it may be concentrated up to sevenfold compared with maternal plasma in chronic consumption....The relative infant dose, the amount absorbed, has been estimated to be 2.5% (range 0.4%–8.7%) of the maternal dose."
Shah S, Schwenk ES, Sondekoppam RV, et al. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Regional Anesthesia & Pain Medicine Published Online First: 03 January 2023. doi: 10.1136/rapm-20
2025-11-05
Clinical trials are evaluating the use of CBD for the treatment of various musculoskeletal conditions. What are some of the musculoskeletal conditions being studied?
The specific musculoskeletal health conditions for which CBD is being evaluated include fibromyalgia, TMJ and myofascial pain, mild to moderate muscle pain, aromatase inhibitor-associated musculoskeletal symptoms (AIMSS), and joint arthritis.
Clinicaltrials.gov
2025-11-04
How does CBD impact the cardiovascular system?
CBD reduces heart rate and blood pressure, and improves vasodilation in models of endothelial dysfunction. Also, CBD reduces inflammation and vascular hyperpermeability in diabetic models.
Page II RL , Allen LA , Kloner RA , Carriker CR , Martel C , Morris AA , Piano MR , Rana JS , Saucedo JF, et al. Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association - Originally published5 Aug 2020https://doi.org/10.1161/CIR.0000000000000883Circulation. 2020;142:e131–e152
2025-11-03
Which meal improves CBD bioavailability more - a high fat or a high carbohydrate meal?
Data from clinical studies indicate that "..a prior high-fat meal enhances CBD bioavailability more than an energy matched high-carbohydrate meal. Therefore, timing CBD ingestion after high-fat meals may be an advantageous strategy to maximise the efficacy of CBD supplementation. "
Cunha MFD, Funnell MP, Johnson DA, Nickels M, Bailey SJ, Heaney LM, and James LJ (2025). A prior high-fat meal increases plasma cannabidiol concentrations compared to an isoenergetic high- carbohydrate meal in healthy young participants: a randomised crossover study. Proceedings of the Nutrition Society 84(OCE4): E254. doi: 10.1017/S0029665125101262

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