Today’s Answer of the Day

Leah Roach August 27, 2019

	Does methadone alter cardiac conduction?
	Yes. Methadone is known to prolong QTc intervals in up to 16% of patients.Studies have shown a linear dose response curve, with higher doses leading to a higher propensity for QTc prolongation.This has led to an FDA “black box” warning for methadone and the recommendation for routine ECG monitoring.