What is the half life of CBD? How does it compare to the half life of THC? |
The half life of CBD is 18-32 hours, which is similar to the half life of THC of 20-30 hours. Both CBD and THC are distributed to fatty tissues and highly perfused organs such as brain, heart, lung, and liver. |
| Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association. Robert L. Page II, Larry A. Allen , Robert A. Kloner , Colin R. Carriker, Catherine Martel, Alanna A. Morris, Mariann R. Piano, Jamal S. Rana, Jorge F. Saucedo, … See all authors. Originally published 5 Aug 2020. https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000883 |
| See the Answer |
Only have a minute but want to Learn something every day®? Sign up to receive The Answer of the Day, bringing featured content from our course library right to your inbox each day.
TheAnswerPage was launched in 1998 to provide daily education to healthcare providers in training and in practice.© 2023 TheAnswerPage.com. Powered by: 
The COVID epidemic has accelerated research of the immune system’s integrated response to viral diseases. This 30-minute video sponsored by the American Osteopathic Association discusses cannabinoids’ impact on optimal immune function. It is presented by physician author, Jeffrey S. Block, MD – founder and principal partner of an independent professional consultancy providing client organizations with advanced scientific guidance. Dr. Block’s industry-wide expertise provides insight by translating the evolving science’s objective evidence-based data into clinical applications.
Jeffrey Sherwood Block, M.D. . is a Board-certified physician anesthesiologist and adjunct Professor at the University of Miami Miller School of Medicine. Additionally, he is a highly awarded horticulturist and certified Master Gardener educator with the University of Florida’s UF/IFAS Extension Program. Dr. Block’s textbook chapter “Endocannabinoid Receptors and Medical Cannabis” (Advanced Therapeutics in Pain Medicine – CRC Press 2020) is a sentinel work on integrated pain management. Block served as the Florida Medical Association’s “Designated Expert on Botanical Medicines” authoring mandated physician education; and in 2014 was appointed by Florida’s Surgeon General to determine the rules for Florida’s first cannabis law. His consultancy’s demonstrated insight and responsible leadership are valued by both allied professionals and new industries seeking knowledge of future uses for Cannabinoid medicines.
Contact: DocBlock@NurturingNature.com
Website: https://nurturingnature.com
E.V. Berdyshev, 2000. Cannabinoid receptors and the regulation of immune response. Chemistry and Physics of Lipids 108 (2000) 169–190; www.elsevier.com/locate/chemphyslip
Biles, Mary 2019. Cannabis and the Immune System – A Complex Balancing Act. Project CBD (May 8, 2019).
Block, Jeffrey S., 2019. Endogenous Cannabinoid Receptors and Medical Cannabis. (pre-publication chapter) Advanced Therapeutics in Pain Medicine, January 2021. CRC Press.
Cabral, Guy A., Rogers, Thomas J., and Lichtman, Aron H., 2015. Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function. J Neuroimmune Pharmacol. 2015; 10(2): 193–203. Published online 2015 Jun 9. doi: 10.1007/s11481-015-9615-z
Centers for Disease Control and Prevention. CDC Urges Clinicians to Report Possible Cases of Unexplained Vaping-associated Pulmonary Illness to their State/Local Health Department. Clinician Outreach and Communication Activity. 2019. Published August 14, 2019.
Hernández-Cervantes R., Méndez-Díaz M., Prospéro-García Ó., and Morales-Montor J. 2017. Immunoregulatory Role of Cannabinoids during Infectious Disease. Neuroimmunomodulation 2017;24:183–199.
Klein TW (2005) Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 5, 400–411.
Li et al. 2019, Cell 176, 459-467.
James M. Nichols and Barbara L.F. Kaplan, 2020. Immune Responses Regulated by Cannabidiol. Cannabis and Cannabinoid Research, Vol. 5, No. 1
National Academies of Science, Engineering and Medicine. The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Washington, DC: The National Academies Press; 2017.
Pacher P, Kunos G. Modulating the endocannabinoid system in human health and disease–successes and failures. FEBS J. 2013;280(9):1918-1943.
Shmerlig, Robert H., MD, 2015. Senior Faculty Editor. First, Do No Harm. Harvard Health Publishing.
Siddappa N. Byrareddy, Mahesh Mohan, 2020. SARS-CoV2 induced respiratory distress: Can cannabinoids be added to anti-viral therapies to reduce lung inflammation? Brain, Behavior, and Immunity 87 (2020) 120–121.
References:
What is the endocannabinoid system?
What are the components of the endocannabinoid system?
What are the two most well studied endocannabinoids?
What are the receptors of the endocannabinoid system?
Describe cannabinoid receptor -1.
Describe cannabinoid receptor -2.
Respiratory depression is associated with the overdose of opioids or benzodiazepines. Is respiratory depression associated with the overdose of cannabinoids?
What are phytocannabinoids?
The terms cannabis, marijuana and hemp are often used interchangeably; however, the terms actually have different meanings. What is cannabis? What is marijuana? What is hemp? Is the hemp plant a cannabis plant?
What are terpenes (terpenoids)?
Briefly describe the health effects of delta-9-tetrahydrocannabinol.
In 2017, the National Academies of Sciences, Engineering and Medicine(NASEM) published the Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Did the results of the research indicate that cannabis-based products are effective?
