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Monthly Archives

August 2020

AOTD
August 31, 2020

Today’s Answer of the Day

Does smoking marijuana impact the metabolism of theophylline? It may. Reports have indicated that smoking marijuana may increase the clearance of theophylline. Note: this effect appears to be a direct…
AOTD
August 30, 2020

Today’s Answer of the Day

Do the hydrocarbons in marijuana smoke impact drug metabolism? Possibly. Similar to cigarette smoke, the hydrocarbons in marijuana smoke appear to induce the activity of some cytochromes, including CYP1A2. See…
AOTD
August 29, 2020

Today’s Answer of the Day

What criteria should be used when selecting a CBD hemp product? According to a 2019 Mayo Clinic publication, the following 4 questions should be asked, and the answers to each…
AOTD
August 28, 2020

Today’s Answer of the Day

Is full spectrum CBD the same as whole plant CBD? No. Whole plant CBD contains fats, waxes and fibrous materials not found in full spectrum CBD. See Answer See Answer
AOTD
August 27, 2020

Today’s Answer of the Day

Is the plasma concentration of Epidiolex (CBD) affected by co-administration of high fat/high calorie food? Yes. It has been that if CBD is co-administered with a high fat/high calorie meal,…
AOTD
August 26, 2020

Today’s Answer of the Day

Describe the exact mechanism of action of Epidiolex. According to the Epidiolex FDA Approved Package Insert, (Greenwich Biosciences, Inc.), the precise mechanism(s) by which Epidiolex exerts its anticonvulsant effects in…
AOTD
August 25, 2020

Today’s Answer of the Day

Have the results of studies examining the impact of maternal marijuana use identified a unique phenotypic congenital anomaly? Studies evaluating maternal use of marijuana have not found a unique phenotypic…
AOTD
August 24, 2020

Today’s Answer of the Day

Changes in fetal growth have been described in some epidemiological studies examining the impact of maternal use of marijuana. Do the longā€term patterns of physical growth appear to be affected?…
AOTD
August 23, 2020

Today’s Answer of the Day

What is the safety profile of Olinvyk? According to an August 7, 2020 FDA news release, "The safety profile of Olinvyk is similar to other opioids. As with other opioids,…
AOTD
August 22, 2020

Today’s Answer of the Day

What is oliceridine (Olinvyk)? Is it a new FDA-approved opioid? According to an August 7, 2020 FDA news release, "the FDA approved Olinvyk (oliceridine), an opioid agonist for the management…