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Monthly Archives

August 2019

AOTD
August 18, 2019

Today’s Answer of the Day

What is the pharmacokinetic profile of methadone? Methadone acts as a mu opioid agonist and an NMDA antagonist. The half-life of methadone ranges from 8 to 90 hours with large…
AOTD
August 17, 2019

Today’s Answer of the Day

When handing off opioid prescribing responsibilities to specialty services, what are the ethics and etiquette involved? Communication between the prescribing physician and specialty service is paramount to a seamless transition.…
AOTD
August 16, 2019

Today’s Answer of the Day

Do cancer patients get addicted to opioids? Do they abuse opioids? For cancer and non-cancer patients, psychosocial factors play a contributory role in the propensity for the development of addiction…
AOTD
August 15, 2019

Today’s Answer of the Day

What is end of dose failure pain? End of dose failure pain is breakthrough pain that develops because the dosing of the around-the-clock analgesic medication is scheduled too far apart…
AOTD
August 14, 2019

Today’s Answer of the Day

What is incident breakthrough pain? Incident pain is defined as pain directly related to an event or an activity performed by the patient. Examples of situations in which incident pain…
AOTD
August 13, 2019

Today’s Answer of the Day

What is spontaneous breakthough pain? Spontaneous breakthrough pain is an unpredictable and sporadic pain without clear relationships to particular events or procedures. This type of pain is difficult to treat…
AOTD
August 12, 2019

Today’s Answer of the Day

What are the three different categories of breakthrough pain? There are three categories of breakthrough pain: spontaneous, incident and end-of-dose failure. See Answer See Answer
AOTD
August 11, 2019

Today’s Answer of the Day

Could cannabinoid therapy modulate the production of excessive saliva in ALS patients? Patients suffering from ALS have difficulty controlling and swallowing their saliva, often resulting in distress and inconvenience to…
AOTD
August 10, 2019

Today’s Answer of the Day

What does it mean to establish medical necessity in a patient who is being considered for opioid therapy? It is essential to establish medical necessity prior to initiation of opioid…
AOTD
August 9, 2019

Today’s Answer of the Day

How can the effectiveness of opioid therapy be assessed? There are several tools that can assist a clinician in evaluating the effectiveness of opioid therapy. The most obvious is pain…