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Monthly Archives

August 2019

AOTD
August 31, 2019

Today’s Answer of the Day

What is the pharmacologic profile of cannabis when it is smoked? When herbal cannabis is smoked, the active ingredients in cannabis are vaporized by the heat of combustion and inhaled.Inhaled…
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AOTD
August 30, 2019

Today’s Answer of the Day

The pharmacological properties of cannabichromene have been investigated.What have the studies shown? Cannabichromene (CBC) is a potent anadamide uptake inhibitor and thus may modulate the endocannabinoid system similarly to CBD.In…
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AOTD
August 29, 2019

Today’s Answer of the Day

The pharmacological properties of cannabinol have been investigated.What have the studies shown? Cannabinol (CBN) is the oxidative by-product of THC and appears after long storage. It is a weaker partial…
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AOTD
August 28, 2019

Today’s Answer of the Day

It is the mixture of phytocannabinoids, terpenes and other active components present in a cannabis product that ultimately determines the therapeutic effects and side effects.Does CBD affect THC absorption and…
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AOTD
August 27, 2019

Today’s Answer of the Day

Does methadone alter cardiac conduction? Yes. Methadone is known to prolong QTc intervals in up to 16% of patients.Studies have shown a linear dose response curve, with higher doses leading…
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AOTD
August 26, 2019

Today’s Answer of the Day

How have medical advances altered opioid use in cancer patients? Cancer is no longer considered a "terminal disease."Because of significant advances in surgical, radiation, and chemotherapeutic treatments, more than 50%…
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AOTD
August 25, 2019

Today’s Answer of the Day

What are terpenes (or terpenoids)? Terpenes are aromatic components produced in the glandular part of the cannabis plant's flower bud.Unlike cannabinoids, which are only manufactured by the cannabis plant, terpenes…
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AOTD
August 24, 2019

Today’s Answer of the Day

Describe cannabinoid receptor-2(CB2). Similar to CB1, the CB2 receptor is a G protein receptor that serves as a target for endocannabinoids and phytocannabinoids.These CB2 receptors are primarily immunomodulatory and anti-inflammatory.…
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AOTD
August 20, 2019

Today’s Answer of the Day

Who are the principal prescribers of opioids in the United States? As a group, primary care physicians are the largest prescribers of opioids ( including both short-acting and long-acting opioid)…
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AOTD
August 19, 2019

Today’s Answer of the Day

What is cross-addiction? The concept of cross-addiction suggests that a person addicted to one reinforcing substance is at a higher risk for addiction to other reinforcing substances. This concept is…
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